Zhao, Jinghui

mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Dec 2015 - 15790-7 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1091-6490

10.1073/pnas.1521919112 doi


Animals
Autophagy
Blotting, Western
Cells, Cultured
HEK293 Cells
Humans
Hydroxymethylglutaryl-CoA Synthase--metabolism
Immunosuppressive Agents--pharmacology
Naphthyridines--pharmacology
Proteasome Endopeptidase Complex--metabolism
Proteolysis--drug effects
Sirolimus--pharmacology
TOR Serine-Threonine Kinases--antagonists & inhibitors
Time Factors
Ubiquitin--metabolism
Ubiquitination--drug effects