TY - GEN AU - Spagnolo,Fabrizio AU - Rinaldi,Conrad AU - Sajorda,Dannah Rae AU - Dykhuizen,Daniel E TI - Evolution of Resistance to Continuously Increasing Streptomycin Concentrations in Populations of Escherichia coli SN - 1098-6596 PY - 2016///1213 KW - Anti-Bacterial Agents KW - administration & dosage KW - Biological Evolution KW - Drug Resistance, Bacterial KW - drug effects KW - Escherichia coli KW - Escherichia coli Proteins KW - genetics KW - Microbial Sensitivity Tests KW - Mutation KW - Polymorphism, Single Nucleotide KW - Ribosomal Proteins KW - Streptomycin N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1128/AAC.01359-15 ER -