TY  - GEN
AU  - Chang,Jianhui
AU  - Wang,Yingying
AU  - Shao,Lijian
AU  - Laberge,Remi-Martin
AU  - Demaria,Marco
AU  - Campisi,Judith
AU  - Janakiraman,Krishnamurthy
AU  - Sharpless,Norman E
AU  - Ding,Sheng
AU  - Feng,Wei
AU  - Luo,Yi
AU  - Wang,Xiaoyan
AU  - Aykin-Burns,Nukhet
AU  - Krager,Kimberly
AU  - Ponnappan,Usha
AU  - Hauer-Jensen,Martin
AU  - Meng,Aimin
AU  - Zhou,Daohong
TI  - Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
SN  - 1546-170X
PY  - 2016///0524
KW  - Aniline Compounds
KW  - pharmacology
KW  - Animals
KW  - Antineoplastic Agents
KW  - Antiviral Agents
KW  - Apoptosis
KW  - drug effects
KW  - B-Lymphocytes
KW  - Blotting, Western
KW  - Cell Cycle
KW  - Cell Line
KW  - Cell Survival
KW  - Cellular Senescence
KW  - Colony-Forming Units Assay
KW  - Cyclin-Dependent Kinase Inhibitor p16
KW  - DNA Damage
KW  - Ganciclovir
KW  - Gene Knockdown Techniques
KW  - Hematopoietic Stem Cells
KW  - Humans
KW  - Mice
KW  - Microscopy
KW  - Muscle, Skeletal
KW  - cytology
KW  - Myoblasts
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - genetics
KW  - RNA, Messenger
KW  - Rejuvenation
KW  - Sulfonamides
KW  - Whole-Body Irradiation
KW  - bcl-X Protein
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1038/nm.4010
ER  -