Chang, Jianhui

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice. [electronic resource] - Nature medicine Jan 2016 - 78-83 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1546-170X

10.1038/nm.4010 doi


Aniline Compounds--pharmacology
Animals
Antineoplastic Agents--pharmacology
Antiviral Agents--pharmacology
Apoptosis--drug effects
B-Lymphocytes--drug effects
Blotting, Western
Cell Cycle
Cell Line
Cell Survival--drug effects
Cellular Senescence
Colony-Forming Units Assay
Cyclin-Dependent Kinase Inhibitor p16--drug effects
DNA Damage
Ganciclovir--pharmacology
Gene Knockdown Techniques
Hematopoietic Stem Cells--drug effects
Humans
Mice
Microscopy
Muscle, Skeletal--cytology
Myoblasts--drug effects
Proto-Oncogene Proteins c-bcl-2--genetics
RNA, Messenger--drug effects
Rejuvenation
Sulfonamides--pharmacology
Whole-Body Irradiation
bcl-X Protein--genetics