Hirata, Yasuko

Interaction between a Domain of the Negative Regulator of the Ras-ERK Pathway, SPRED1 Protein, and the GTPase-activating Protein-related Domain of Neurofibromin Is Implicated in Legius Syndrome and Neurofibromatosis Type 1. [electronic resource] - The Journal of biological chemistry Feb 2016 - 3124-34 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M115.703710 doi


Adaptor Proteins, Signal Transducing
Amino Acid Transport System A
Cafe-au-Lait Spots--genetics
Epidermal Growth Factor--metabolism
Female
Genes, Reporter
Genetic Association Studies
HEK293 Cells
Humans
Intracellular Signaling Peptides and Proteins--chemistry
Kinetics
MAP Kinase Signaling System
Male
Membrane Proteins--chemistry
Models, Molecular
Mutation, Missense
Neurofibromatosis 1--genetics
Neurofibromin 1--chemistry
Peptide Fragments--chemistry
Point Mutation
Protein Conformation
Protein Interaction Domains and Motifs
Proto-Oncogene Proteins p21(ras)--agonists
Recombinant Fusion Proteins--chemistry