Interaction between a Domain of the Negative Regulator of the Ras-ERK Pathway, SPRED1 Protein, and the GTPase-activating Protein-related Domain of Neurofibromin Is Implicated in Legius Syndrome and Neurofibromatosis Type 1. [electronic resource]
- The Journal of biological chemistry Feb 2016
- 3124-34 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1083-351X
10.1074/jbc.M115.703710 doi
Adaptor Proteins, Signal Transducing Amino Acid Transport System A Cafe-au-Lait Spots--genetics Epidermal Growth Factor--metabolism Female Genes, Reporter Genetic Association Studies HEK293 Cells Humans Intracellular Signaling Peptides and Proteins--chemistry Kinetics MAP Kinase Signaling System Male Membrane Proteins--chemistry Models, Molecular Mutation, Missense Neurofibromatosis 1--genetics Neurofibromin 1--chemistry Peptide Fragments--chemistry Point Mutation Protein Conformation Protein Interaction Domains and Motifs Proto-Oncogene Proteins p21(ras)--agonists Recombinant Fusion Proteins--chemistry