Raymond, A D

Microglia-derived HIV Nef+ exosome impairment of the blood-brain barrier is treatable by nanomedicine-based delivery of Nef peptides. [electronic resource] - Journal of neurovirology Apr 2016 - 129-39 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1538-2443

10.1007/s13365-015-0397-0 doi


Blood-Brain Barrier--drug effects
Cell Line
Chemokine CCL5--genetics
Drug Carriers--pharmacology
Endothelial Cells--cytology
Escherichia coli--genetics
Exosomes--metabolism
Gene Expression Regulation
Genes, Reporter
Green Fluorescent Proteins--genetics
HEK293 Cells
HIV-1--chemistry
Humans
Interleukins--genetics
Magnetite Nanoparticles--chemistry
Microglia--cytology
Models, Biological
Peptides--chemical synthesis
Signal Transduction
Transfection
Transgenes
nef Gene Products, Human Immunodeficiency Virus--antagonists & inhibitors