TY  - GEN
AU  - Valletta,Simona
AU  - Dolatshad,Hamid
AU  - Bartenstein,Matthias
AU  - Yip,Bon Ham
AU  - Bello,Erica
AU  - Gordon,Shanisha
AU  - Yu,Yiting
AU  - Shaw,Jacqueline
AU  - Roy,Swagata
AU  - Scifo,Laura
AU  - Schuh,Anna
AU  - Pellagatti,Andrea
AU  - Fulga,Tudor A
AU  - Verma,Amit
AU  - Boultwood,Jacqueline
TI  - ASXL1 mutation correction by CRISPR/Cas9 restores gene function in leukemia cells and increases survival in mouse xenografts
SN  - 1949-2553
PY  - 2016///1107
KW  - Animals
KW  - Base Sequence
KW  - CRISPR-Associated Proteins
KW  - genetics
KW  - CRISPR-Cas Systems
KW  - Cell Differentiation
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Clustered Regularly Interspaced Short Palindromic Repeats
KW  - Codon, Nonsense
KW  - Gene Expression Regulation, Leukemic
KW  - Genetic Predisposition to Disease
KW  - Heterografts
KW  - Homozygote
KW  - Humans
KW  - Interleukin Receptor Common gamma Subunit
KW  - deficiency
KW  - Leukemia, Myelogenous, Chronic, BCR-ABL Positive
KW  - Mice, Inbred NOD
KW  - Mice, Knockout
KW  - Mice, SCID
KW  - Molecular Sequence Data
KW  - Neoplasm Transplantation
KW  - Phenotype
KW  - Polycomb Repressive Complex 2
KW  - Repressor Proteins
KW  - Time Factors
KW  - Tumor Suppressor Proteins
KW  - Ubiquitin Thiolesterase
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.18632/oncotarget.6392
ER  -