TY - GEN AU - Gassen,Nils C AU - Fries,Gabriel R AU - Zannas,Anthony S AU - Hartmann,Jakob AU - Zschocke,Jürgen AU - Hafner,Kathrin AU - Carrillo-Roa,Tania AU - Steinbacher,Jessica AU - Preißinger,S Nicole AU - Hoeijmakers,Lianne AU - Knop,Matthias AU - Weber,Frank AU - Kloiber,Stefan AU - Lucae,Susanne AU - Chrousos,George P AU - Carell,Thomas AU - Ising,Marcus AU - Binder,Elisabeth B AU - Schmidt,Mathias V AU - Rüegg,Joëlle AU - Rein,Theo TI - Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine SN - 1937-9145 PY - 2016///0907 KW - Animals KW - Antidepressive Agents KW - pharmacology KW - Brain-Derived Neurotrophic Factor KW - biosynthesis KW - DNA (Cytosine-5-)-Methyltransferase 1 KW - DNA (Cytosine-5-)-Methyltransferases KW - genetics KW - DNA Methylation KW - drug effects KW - Depression KW - drug therapy KW - Epigenesis, Genetic KW - HEK293 Cells KW - Humans KW - Mice KW - Paroxetine KW - Phosphorylation KW - Tacrolimus Binding Proteins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/scisignal.aac7695 ER -