TY - GEN AU - Barlowe,C K AU - Williams,M E AU - Rabinowitz,J C AU - Appling,D R TI - Site-directed mutagenesis of yeast C1-tetrahydrofolate synthase: analysis of an overlapping active site in a multifunctional enzyme SN - 0006-2960 PY - 1989///0629 KW - Amino Acid Sequence KW - Aminohydrolases KW - genetics KW - Base Sequence KW - Binding Sites KW - Catalysis KW - Cloning, Molecular KW - Cysteine KW - metabolism KW - Endonucleases KW - Formate-Tetrahydrofolate Ligase KW - Kinetics KW - Ligases KW - Methenyltetrahydrofolate Cyclohydrolase KW - Methylenetetrahydrofolate Dehydrogenase (NADP) KW - Molecular Sequence Data KW - Multienzyme Complexes KW - Mutation KW - Oxidoreductases KW - Plasmids KW - RNA, Messenger KW - Recombinant Fusion Proteins KW - Restriction Mapping KW - Saccharomyces cerevisiae KW - enzymology KW - Single-Strand Specific DNA and RNA Endonucleases KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1021/bi00431a020 ER -