TY - GEN AU - Wu,An-Guo AU - Wong,Vincent Kam-Wai AU - Zeng,Wu AU - Liu,Liang AU - Law,Betty Yuen-Kwan TI - Identification of novel autophagic Radix Polygalae fraction by cell membrane chromatography and UHPLC-(Q)TOF-MS for degradation of neurodegenerative disease proteins SN - 2045-2322 PY - 2016///0919 KW - Animals KW - Autophagy KW - drug effects KW - Cell Membrane KW - chemistry KW - Chromatography, High Pressure Liquid KW - Drugs, Chinese Herbal KW - isolation & purification KW - Huntingtin Protein KW - Inhibitory Concentration 50 KW - Mice, Knockout KW - Nerve Tissue Proteins KW - metabolism KW - Neurodegenerative Diseases KW - drug therapy KW - Nuclear Proteins KW - PC12 Cells KW - Polygala KW - Proteolysis KW - Rats KW - Saponins KW - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization KW - Triterpenes KW - alpha-Synuclein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/srep17199 ER -