Molecular mechanism mediating cytotoxic activity of axitinib in sunitinib-resistant human renal cell carcinoma cells. [electronic resource]
- Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico Sep 2016
- 893-900 p. digital
Publication Type: Journal Article
1699-3055
10.1007/s12094-015-1457-x doi
Animals Antineoplastic Agents--pharmacology Axitinib Blotting, Western Carcinoma, Renal Cell--pathology Cell Line, Tumor Cell Proliferation--genetics Drug Resistance, Neoplasm--drug effects Enzyme-Linked Immunosorbent Assay Humans Imidazoles--pharmacology Immunohistochemistry Indazoles--pharmacology Indoles--pharmacology Kidney Neoplasms--pathology Mice Mice, Inbred BALB C Mice, Nude Mitogen-Activated Protein Kinase 1--genetics Mitogen-Activated Protein Kinase 3--genetics Protein Kinase Inhibitors--pharmacology Pyrroles--pharmacology Sunitinib Vascular Endothelial Growth Factor Receptor-2--genetics Xenograft Model Antitumor Assays