Tardito, Saverio

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma. [electronic resource] - Nature cell biology Dec 2015 - 1556-68 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1476-4679

10.1038/ncb3272 doi


Animals
Astrocytes--cytology
Blotting, Western
Brain Neoplasms--genetics
Cell Line, Tumor
Cell Proliferation
Cells, Cultured
Citric Acid Cycle
Coculture Techniques
Female
Glioblastoma--genetics
Glutamate-Ammonia Ligase--genetics
Glutamic Acid--metabolism
Glutamine--metabolism
Humans
Male
Mice, Inbred NOD
Mice, SCID
Models, Biological
Neoplastic Stem Cells--metabolism
Nucleotides--biosynthesis
Rats, Sprague-Dawley
Reverse Transcriptase Polymerase Chain Reaction
Transplantation, Heterologous