TY - GEN AU - Buontempo,Francesca AU - Orsini,Ester AU - Lonetti,Annalisa AU - Cappellini,Alessandra AU - Chiarini,Francesca AU - Evangelisti,Camilla AU - Evangelisti,Cecilia AU - Melchionda,Fraia AU - Pession,Andrea AU - Bertaina,Alice AU - Locatelli,Franco AU - Bertacchini,Jessika AU - Neri,Luca Maria AU - McCubrey,James A AU - Martelli,Alberto Maria TI - Synergistic cytotoxic effects of bortezomib and CK2 inhibitor CX-4945 in acute lymphoblastic leukemia: turning off the prosurvival ER chaperone BIP/Grp78 and turning on the pro-apoptotic NF-κB SN - 1949-2553 PY - 2016///1213 KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - drug effects KW - Blotting, Western KW - Bortezomib KW - Casein Kinase II KW - antagonists & inhibitors KW - Cell Line, Tumor KW - Cell Survival KW - Drug Synergism KW - Endoplasmic Reticulum Chaperone BiP KW - Endoplasmic Reticulum Stress KW - Heat-Shock Proteins KW - metabolism KW - Humans KW - Jurkat Cells KW - Microscopy, Fluorescence KW - Naphthyridines KW - Neoplastic Stem Cells KW - Phenazines KW - Precursor B-Cell Lymphoblastic Leukemia-Lymphoma KW - blood KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma KW - Precursor T-Cell Lymphoblastic Leukemia-Lymphoma KW - Transcription Factor RelA KW - Unfolded Protein Response N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.18632/oncotarget.6361 ER -