TY  - GEN
AU  - Louis,Marcell
AU  - Hofmann,Kay
AU  - Broemer,Meike
TI  - Evolutionary Loss of Activity in De-Ubiquitylating Enzymes of the OTU Family
SN  - 1932-6203
PY  - 2016///0620
KW  - Amino Acid Sequence
KW  - Amino Acid Substitution
KW  - Animals
KW  - Apoptosis
KW  - genetics
KW  - Binding Sites
KW  - Catalytic Domain
KW  - Conserved Sequence
KW  - Cysteine
KW  - metabolism
KW  - Drosophila Proteins
KW  - Drosophila melanogaster
KW  - Evolution, Molecular
KW  - Gene Expression Regulation
KW  - Humans
KW  - Inhibitor of Apoptosis Proteins
KW  - antagonists & inhibitors
KW  - Molecular Sequence Data
KW  - Protein Binding
KW  - RNA, Small Interfering
KW  - Sequence Alignment
KW  - Sequence Homology, Amino Acid
KW  - Serine
KW  - Ubiquitin
KW  - Ubiquitin-Specific Proteases
KW  - Ubiquitination
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0143227
ER  -