TY - GEN AU - Post,Anke AU - Smart,Trevor S AU - Krikke-Workel,Judith AU - Dawson,Gerard R AU - Harmer,Catherine J AU - Browning,Michael AU - Jackson,Kimberley AU - Kakar,Rishi AU - Mohs,Richard AU - Statnick,Michael AU - Wafford,Keith AU - McCarthy,Andrew AU - Barth,Vanessa AU - Witkin,Jeffrey M TI - A Selective Nociceptin Receptor Antagonist to Treat Depression: Evidence from Preclinical and Clinical Studies SN - 1740-634X PY - 2018///0102 KW - Adolescent KW - Adult KW - Aged KW - Animals KW - Anti-Anxiety Agents KW - pharmacology KW - Chlordiazepoxide KW - Depression KW - drug therapy KW - Disease Models, Animal KW - Double-Blind Method KW - Eye Movements KW - drug effects KW - Female KW - Follow-Up Studies KW - Humans KW - Male KW - Mice KW - Middle Aged KW - Narcotic Antagonists KW - therapeutic use KW - Prefrontal Cortex KW - Pregnancy KW - Pyrans KW - Rats KW - Rats, Sprague-Dawley KW - Receptors, Opioid KW - metabolism KW - Spiro Compounds KW - Young Adult KW - Nociceptin Receptor N1 - Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial UR - https://doi.org/10.1038/npp.2015.348 ER -