TY  - GEN
AU  - Sampson,Valerie B
AU  - Vetter,Nancy S
AU  - Kamara,Davida F
AU  - Collier,Anderson B
AU  - Gresh,Renee C
AU  - Kolb,E Anders
TI  - Vorinostat Enhances Cytotoxicity of SN-38 and Temozolomide in Ewing Sarcoma Cells and Activates STAT3/AKT/MAPK Pathways
SN  - 1932-6203
PY  - 2016///0628
KW  - Acetylation
KW  - drug effects
KW  - Antineoplastic Agents
KW  - toxicity
KW  - Apoptosis
KW  - Camptothecin
KW  - analogs & derivatives
KW  - Caspase 3
KW  - metabolism
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Cell Survival
KW  - DNA Damage
KW  - Dacarbazine
KW  - G1 Phase Cell Cycle Checkpoints
KW  - Heterocyclic Compounds, 3-Ring
KW  - pharmacology
KW  - Histone Deacetylase Inhibitors
KW  - Humans
KW  - Hydroxamic Acids
KW  - Irinotecan
KW  - Mitogen-Activated Protein Kinases
KW  - Proto-Oncogene Proteins c-akt
KW  - antagonists & inhibitors
KW  - Reactive Oxygen Species
KW  - STAT3 Transcription Factor
KW  - Sarcoma, Ewing
KW  - Signal Transduction
KW  - Temozolomide
KW  - Tumor Suppressor Protein p53
KW  - Vorinostat
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0142704
ER  -