Sampson, Valerie B <br/><br/>
Vorinostat Enhances Cytotoxicity of SN-38 and Temozolomide in Ewing Sarcoma Cells and Activates STAT3/AKT/MAPK Pathways.  [electronic resource] 

 -  PloS one  2015 
 - e0142704 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1932-6203 
<br/><br/><label>Standard No.: </label>10.1371/journal.pone.0142704  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetylation--drug effects<br/>Antineoplastic Agents--toxicity<br/>Apoptosis--drug effects<br/>Camptothecin--analogs & derivatives<br/>Caspase 3--metabolism<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cell Survival--drug effects<br/>DNA Damage--drug effects<br/>Dacarbazine--analogs & derivatives<br/>G1 Phase Cell Cycle Checkpoints--drug effects<br/>Heterocyclic Compounds, 3-Ring--pharmacology<br/>Histone Deacetylase Inhibitors--toxicity<br/>Humans<br/>Hydroxamic Acids--toxicity<br/>Irinotecan<br/>Mitogen-Activated Protein Kinases--metabolism<br/>Proto-Oncogene Proteins c-akt--antagonists & inhibitors<br/>Reactive Oxygen Species--metabolism<br/>STAT3 Transcription Factor--antagonists & inhibitors<br/>Sarcoma, Ewing--metabolism<br/>Signal Transduction--drug effects<br/>Temozolomide<br/>Tumor Suppressor Protein p53--metabolism<br/>Vorinostat