Handa, Priya

Iron overload results in hepatic oxidative stress, immune cell activation, and hepatocellular ballooning injury, leading to nonalcoholic steatohepatitis in genetically obese mice. [electronic resource] - American journal of physiology. Gastrointestinal and liver physiology Jan 2016 - G117-27 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1522-1547

10.1152/ajpgi.00246.2015 doi


Adaptive Immunity--genetics
Animals
Disease Models, Animal
Immunity, Innate--genetics
Iron Overload--complications
Liver--metabolism
Malondialdehyde--metabolism
Mice
Mice, Obese
Non-alcoholic Fatty Liver Disease--etiology
Obesity--complications
Oxidative Stress--physiology
Reactive Oxygen Species--metabolism
Receptors, Leptin--genetics