Montano, Giorgia <br/><br/>
The hematopoietic tumor suppressor interferon regulatory factor 8 (IRF8) is upregulated by the antimetabolite cytarabine in leukemic cells involving the zinc finger protein ZNF224, acting as a cofactor of the Wilms' tumor gene 1 (WT1) protein.  [electronic resource] 

 -  Leukemia research  Jan 2016 
 - 60-7 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1873-5835 
<br/><br/><label>Standard No.: </label>10.1016/j.leukres.2015.10.014  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antimetabolites, Antineoplastic--pharmacology<br/>Cell Line, Tumor<br/>Cytarabine--pharmacology<br/>Humans<br/>Interferon Regulatory Factors--physiology<br/>Leukemia--pathology<br/>Up-Regulation--drug effects<br/>WT1 Proteins--metabolism<br/>Zinc Fingers