TY  - GEN
AU  - Ling,Yong
AU  - Xu,Chenjun
AU  - Luo,Lin
AU  - Cao,Jingyi
AU  - Feng,Jiao
AU  - Xue,Yu
AU  - Zhu,Qing
AU  - Ju,Caoyun
AU  - Li,Fengzhi
AU  - Zhang,Yihua
AU  - Zhang,Yanan
AU  - Ling,Xiang
TI  - Novel β-Carboline/Hydroxamic Acid Hybrids Targeting Both Histone Deacetylase and DNA Display High Anticancer Activity via Regulation of the p53 Signaling Pathway
SN  - 1520-4804
PY  - 2016///0412
KW  - Acetylation
KW  - drug effects
KW  - Animals
KW  - Antineoplastic Agents
KW  - chemistry
KW  - Apoptosis
KW  - Carbolines
KW  - Cell Proliferation
KW  - Colon
KW  - Colorectal Neoplasms
KW  - drug therapy
KW  - DNA
KW  - metabolism
KW  - Female
KW  - HCT116 Cells
KW  - Histone Deacetylase Inhibitors
KW  - Histone Deacetylases
KW  - Humans
KW  - Hydroxamic Acids
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Mice, Nude
KW  - Rectum
KW  - Signal Transduction
KW  - Tubulin
KW  - Tumor Suppressor Protein p53
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/acs.jmedchem.5b01052
ER  -