Srinivas, Chatla

Novel Etoposide Analogue Modulates Expression of Angiogenesis Associated microRNAs and Regulates Cell Proliferation by Targeting STAT3 in Breast Cancer. [electronic resource] - PloS one 2015 - e0142006 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0142006 doi


Apoptosis--drug effects
Breast Neoplasms--drug therapy
Caspase 9--metabolism
Cell Cycle Checkpoints--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Survival--drug effects
DNA Damage--drug effects
Enzyme Activation--drug effects
Etoposide--analogs & derivatives
Gene Expression Regulation, Neoplastic
Human Umbilical Vein Endothelial Cells--drug effects
Humans
MCF-7 Cells
MicroRNAs--biosynthesis
Models, Molecular
Molecular Docking Simulation
Neovascularization, Pathologic--pathology
Podophyllotoxin--analogs & derivatives
Protein Binding
Proto-Oncogene Proteins c-bcl-2--metabolism
Quinazolines--pharmacology
RNA Interference
RNA, Small Interfering--genetics
STAT3 Transcription Factor--metabolism
Vascular Endothelial Growth Factor A--metabolism