TY - GEN AU - Röllig,Christoph AU - Serve,Hubert AU - Hüttmann,Andreas AU - Noppeney,Richard AU - Müller-Tidow,Carsten AU - Krug,Utz AU - Baldus,Claudia D AU - Brandts,Christian H AU - Kunzmann,Volker AU - Einsele,Hermann AU - Krämer,Alwin AU - Schäfer-Eckart,Kerstin AU - Neubauer,Andreas AU - Burchert,Andreas AU - Giagounidis,Aristoteles AU - Krause,Stefan W AU - Mackensen,Andreas AU - Aulitzky,Walter AU - Herbst,Regina AU - Hänel,Mathias AU - Kiani,Alexander AU - Frickhofen,Norbert AU - Kullmer,Johannes AU - Kaiser,Ulrich AU - Link,Hartmut AU - Geer,Thomas AU - Reichle,Albert AU - Junghanß,Christian AU - Repp,Roland AU - Heits,Frank AU - Dürk,Heinz AU - Hase,Jana AU - Klut,Ina-Maria AU - Illmer,Thomas AU - Bornhäuser,Martin AU - Schaich,Markus AU - Parmentier,Stefani AU - Görner,Martin AU - Thiede,Christian AU - von Bonin,Malte AU - Schetelig,Johannes AU - Kramer,Michael AU - Berdel,Wolfgang E AU - Ehninger,Gerhard TI - Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2, randomised controlled trial SN - 1474-5488 PY - 2016///0418 KW - Adult KW - Age Factors KW - Antibiotics, Antineoplastic KW - therapeutic use KW - Antimetabolites, Antineoplastic KW - Antineoplastic Combined Chemotherapy Protocols KW - adverse effects KW - Chemotherapy, Adjuvant KW - Cytarabine KW - Daunorubicin KW - Disease Progression KW - Disease-Free Survival KW - Double-Blind Method KW - Female KW - Germany KW - Hematopoietic Stem Cell Transplantation KW - Humans KW - Kaplan-Meier Estimate KW - Leukemia, Myeloid, Acute KW - diagnosis KW - Male KW - Middle Aged KW - Neoadjuvant Therapy KW - Niacinamide KW - Phenylurea Compounds KW - Proportional Hazards Models KW - Protein Kinase Inhibitors KW - Recurrence KW - Risk Factors KW - Sorafenib KW - Time Factors KW - Transplantation, Homologous KW - Treatment Outcome N1 - Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/S1470-2045(15)00362-9 ER -