Röllig, Christoph

Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2, randomised controlled trial. [electronic resource] - The Lancet. Oncology Dec 2015 - 1691-9 p. digital

Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

1474-5488

10.1016/S1470-2045(15)00362-9 doi


Adult
Age Factors
Antibiotics, Antineoplastic--therapeutic use
Antimetabolites, Antineoplastic--therapeutic use
Antineoplastic Combined Chemotherapy Protocols--adverse effects
Chemotherapy, Adjuvant
Cytarabine--therapeutic use
Daunorubicin--therapeutic use
Disease Progression
Disease-Free Survival
Double-Blind Method
Female
Germany
Hematopoietic Stem Cell Transplantation
Humans
Kaplan-Meier Estimate
Leukemia, Myeloid, Acute--diagnosis
Male
Middle Aged
Neoadjuvant Therapy--adverse effects
Niacinamide--adverse effects
Phenylurea Compounds--adverse effects
Proportional Hazards Models
Protein Kinase Inhibitors--adverse effects
Recurrence
Risk Factors
Sorafenib
Time Factors
Transplantation, Homologous
Treatment Outcome