TY  - GEN
AU  - Iacobucci,Ilaria
AU  - Di Rorà,Andrea Ghelli Luserna
AU  - Falzacappa,Maria Vittoria Verga
AU  - Agostinelli,Claudio
AU  - Derenzini,Enrico
AU  - Ferrari,Anna
AU  - Papayannidis,Cristina
AU  - Lonetti,Annalisa
AU  - Righi,Simona
AU  - Imbrogno,Enrica
AU  - Pomella,Silvia
AU  - Venturi,Claudia
AU  - Guadagnuolo,Viviana
AU  - Cattina,Federica
AU  - Ottaviani,Emanuela
AU  - Abbenante,Maria Chiara
AU  - Vitale,Antonella
AU  - Elia,Loredana
AU  - Russo,Domenico
AU  - Zinzani,Pier Luigi
AU  - Pileri,Stefano
AU  - Pelicci,Pier Giuseppe
AU  - Martinelli,Giovanni
TI  - In vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemia
SN  - 1756-8722
PY  - 2016///0711
KW  - Animals
KW  - Apoptosis
KW  - drug effects
KW  - Benzodiazepinones
KW  - pharmacology
KW  - Blotting, Western
KW  - Cell Cycle
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - Checkpoint Kinase 1
KW  - Dose-Response Relationship, Drug
KW  - Gene Expression Profiling
KW  - methods
KW  - Gene Expression Regulation, Leukemic
KW  - Humans
KW  - Leukemia, Experimental
KW  - drug therapy
KW  - Mice, Inbred C57BL
KW  - Microscopy, Fluorescence
KW  - Neoplastic Stem Cells
KW  - Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
KW  - genetics
KW  - Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
KW  - Protein Kinase Inhibitors
KW  - Protein Kinases
KW  - Pyrazoles
KW  - Survival Analysis
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1186/s13045-015-0206-5
ER  -