Iacobucci, Ilaria

In vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemia. [electronic resource] - Journal of hematology & oncology Nov 2015 - 125 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1756-8722

10.1186/s13045-015-0206-5 doi


Animals
Apoptosis--drug effects
Benzodiazepinones--pharmacology
Blotting, Western
Cell Cycle--drug effects
Cell Line, Tumor
Cell Survival--drug effects
Checkpoint Kinase 1
Dose-Response Relationship, Drug
Gene Expression Profiling--methods
Gene Expression Regulation, Leukemic--drug effects
Humans
Leukemia, Experimental--drug therapy
Mice, Inbred C57BL
Microscopy, Fluorescence
Neoplastic Stem Cells--drug effects
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma--genetics
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
Protein Kinase Inhibitors--pharmacology
Protein Kinases--genetics
Pyrazoles--pharmacology
Survival Analysis