TY - GEN AU - Signore,Sergio AU - Sorrentino,Andrea AU - Borghetti,Giulia AU - Cannata,Antonio AU - Meo,Marianna AU - Zhou,Yu AU - Kannappan,Ramaswamy AU - Pasqualini,Francesco AU - O'Malley,Heather AU - Sundman,Mark AU - Tsigkas,Nikolaos AU - Zhang,Eric AU - Arranto,Christian AU - Mangiaracina,Chiara AU - Isobe,Kazuya AU - Sena,Brena F AU - Kim,Junghyun AU - Goichberg,Polina AU - Nahrendorf,Matthias AU - Isom,Lori L AU - Leri,Annarosa AU - Anversa,Piero AU - Rota,Marcello TI - Late Na(+) current and protracted electrical recovery are critical determinants of the aging myopathy SN - 2041-1723 PY - 2016///0510 KW - Action Potentials KW - Aging KW - metabolism KW - Animals KW - Calcium KW - Cardiomyopathies KW - Collagen KW - Disease Models, Animal KW - Heart KW - physiopathology KW - Heart Ventricles KW - Mice KW - Mice, Knockout KW - Myocardial Contraction KW - Myocardium KW - Myocytes, Cardiac KW - Patch-Clamp Techniques KW - Sarcoplasmic Reticulum KW - Sodium KW - Voltage-Gated Sodium Channel beta-1 Subunit KW - genetics N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1038/ncomms9803 ER -