Xu, Yue-Mei HRD1 suppresses the growth and metastasis of breast cancer cells by promoting IGF-1R degradation. [electronic resource] - Oncotarget Dec 2015 - 42854-67 p. digital Publication Type: Journal Article; Research Support, Non-U.S. Gov't ISSN: 1949-2553 Standard No.: 10.18632/oncotarget.5733 doi Subjects--Topical Terms: AgedAnimalsBlotting, WesternBreast Neoplasms--metabolismCell Line, TumorCell Proliferation--physiologyChromatin ImmunoprecipitationDown-RegulationEpithelial-Mesenchymal Transition--physiologyFemaleGene Expression Regulation, Neoplastic--physiologyHeterograftsHumansImmunohistochemistryKaplan-Meier EstimateMiceMice, NudeMiddle AgedNeoplasm Invasiveness--pathologyRNA, Small InterferingReal-Time Polymerase Chain ReactionReceptor, IGF Type 1--metabolismTissue Array AnalysisTransfectionUbiquitin-Protein Ligases--metabolism