TY  - GEN
AU  - Yosaatmadja,Yuliana
AU  - Silva,Shevan
AU  - Dickson,James M
AU  - Patterson,Adam V
AU  - Smaill,Jeff B
AU  - Flanagan,Jack U
AU  - McKeage,Mark J
AU  - Squire,Christopher J
TI  - Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed
SN  - 1095-8657
PY  - 2016///0913
KW  - Acrylamides
KW  - metabolism
KW  - Aniline Compounds
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Crystallography, X-Ray
KW  - Drug Resistance, Neoplasm
KW  - genetics
KW  - ErbB Receptors
KW  - antagonists & inhibitors
KW  - Erlotinib Hydrochloride
KW  - Gefitinib
KW  - Humans
KW  - Lung Neoplasms
KW  - drug therapy
KW  - Protein Binding
KW  - physiology
KW  - Protein Kinase Inhibitors
KW  - Quinazolines
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.jsb.2015.10.018
ER  -