TY  - GEN
AU  - Zhang,Jian
AU  - Ali,Hamed I
AU  - Bedi,Yudhishtar Singh
AU  - Choudhury,Mahua
TI  - The plasticizer BBP selectively inhibits epigenetic regulator sirtuins
SN  - 1879-3185
PY  - 2016///0307
KW  - Binding Sites
KW  - Crystallography
KW  - Dose-Response Relationship, Drug
KW  - Endocrine Disruptors
KW  - metabolism
KW  - Epigenesis, Genetic
KW  - drug effects
KW  - Gene Expression Regulation
KW  - Hep G2 Cells
KW  - Hepatocytes
KW  - Histone Deacetylase Inhibitors
KW  - Humans
KW  - Hydrogen Bonding
KW  - Ligands
KW  - Mitochondria, Liver
KW  - Molecular Docking Simulation
KW  - NF-E2-Related Factor 2
KW  - genetics
KW  - Nuclear Respiratory Factor 1
KW  - Organelle Biogenesis
KW  - Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
KW  - Phthalic Acids
KW  - Plasticizers
KW  - Protein Binding
KW  - Protein Conformation
KW  - RNA Interference
KW  - Reactive Oxygen Species
KW  - Sirtuin 1
KW  - antagonists & inhibitors
KW  - Sirtuin 3
KW  - Transcription Factors
KW  - Transfection
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.tox.2015.10.004
ER  -