Zhang, Jian <br/><br/>
The plasticizer BBP selectively inhibits epigenetic regulator sirtuins.  [electronic resource] 

 -  Toxicology  Dec 2015 
 - 130-41 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1879-3185 
<br/><br/><label>Standard No.: </label>10.1016/j.tox.2015.10.004  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Binding Sites<br/>Crystallography<br/>Dose-Response Relationship, Drug<br/>Endocrine Disruptors--metabolism<br/>Epigenesis, Genetic--drug effects<br/>Gene Expression Regulation<br/>Hep G2 Cells<br/>Hepatocytes--drug effects<br/>Histone Deacetylase Inhibitors--metabolism<br/>Humans<br/>Hydrogen Bonding<br/>Ligands<br/>Mitochondria, Liver--drug effects<br/>Molecular Docking Simulation<br/>NF-E2-Related Factor 2--genetics<br/>Nuclear Respiratory Factor 1--genetics<br/>Organelle Biogenesis<br/>Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha<br/>Phthalic Acids--metabolism<br/>Plasticizers--metabolism<br/>Protein Binding<br/>Protein Conformation<br/>RNA Interference<br/>Reactive Oxygen Species--metabolism<br/>Sirtuin 1--antagonists & inhibitors<br/>Sirtuin 3--antagonists & inhibitors<br/>Transcription Factors--genetics<br/>Transfection