TY - GEN AU - Sewell,Fiona AU - Ragan,Ian AU - Marczylo,Tim AU - Anderson,Brian AU - Braun,Anne AU - Casey,Warren AU - Dennison,Ngaire AU - Griffiths,David AU - Guest,Robert AU - Holmes,Tom AU - van Huygevoort,Ton AU - Indans,Ian AU - Kenny,Terry AU - Kojima,Hajime AU - Lee,Kyuhong AU - Prieto,Pilar AU - Smith,Paul AU - Smedley,Jason AU - Stokes,William S AU - Wnorowski,Gary AU - Horgan,Graham TI - A global initiative to refine acute inhalation studies through the use of 'evident toxicity' as an endpoint: Towards adoption of the fixed concentration procedure SN - 1096-0295 PY - 2016///1005 KW - Aerosols KW - Animals KW - Behavior, Animal KW - drug effects KW - Consensus KW - Cooperative Behavior KW - Dose-Response Relationship, Drug KW - Endpoint Determination KW - standards KW - Female KW - Guidelines as Topic KW - Humans KW - Inhalation Exposure KW - adverse effects KW - International Cooperation KW - Lethal Dose 50 KW - Male KW - Models, Animal KW - Motor Activity KW - Observer Variation KW - Powders KW - Rats KW - Reproducibility of Results KW - Respiration KW - Time Factors KW - Toxicity Tests, Acute KW - methods KW - Weight Loss N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.yrtph.2015.10.018 ER -