TY - GEN AU - Gregorieff,Alex AU - Liu,Yu AU - Inanlou,Mohammad R AU - Khomchuk,Yuliya AU - Wrana,Jeffrey L TI - Yap-dependent reprogramming of Lgr5(+) stem cells drives intestinal regeneration and cancer SN - 1476-4687 PY - 2016///0426 KW - Adaptor Proteins, Signal Transducing KW - deficiency KW - Adenoma KW - metabolism KW - Animals KW - Cell Cycle Proteins KW - Cell Differentiation KW - radiation effects KW - Cell Survival KW - Cell Transformation, Neoplastic KW - Colonic Neoplasms KW - Disease Models, Animal KW - Epiregulin KW - ErbB Receptors KW - Female KW - Hippo Signaling Pathway KW - Homeostasis KW - Intestinal Mucosa KW - Intestines KW - cytology KW - Male KW - Mice KW - Neoplastic Stem Cells KW - Organoids KW - Paneth Cells KW - Phosphoproteins KW - Protein Serine-Threonine Kinases KW - Radiation, Ionizing KW - Receptors, G-Protein-Coupled KW - Regeneration KW - Stem Cells KW - Wnt Signaling Pathway KW - YAP-Signaling Proteins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/nature15382 ER -