Ma, Shuang <br/><br/>
SKLB-677, an FLT3 and Wnt/β-catenin signaling inhibitor, displays potent activity in models of FLT3-driven AML.  [electronic resource] 

 -  Scientific reports  Oct 2015 
 - 15646 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2045-2322 
<br/><br/><label>Standard No.: </label>10.1038/srep15646  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Animals, Genetically Modified<br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cell Survival--drug effects<br/>Drug Resistance, Neoplasm<br/>Female<br/>G1 Phase Cell Cycle Checkpoints--drug effects<br/>Humans<br/>Isoxazoles--pharmacology<br/>Leukemia, Myeloid, Acute--drug therapy<br/>Mice<br/>Mice, Inbred NOD<br/>Mice, SCID<br/>Phenylurea Compounds--chemistry<br/>Pyrazoles--chemistry<br/>Pyrimidines--chemistry<br/>Urea--analogs & derivatives<br/>Wnt Proteins--antagonists & inhibitors<br/>Wnt Signaling Pathway--drug effects<br/>Zebrafish<br/>beta Catenin--antagonists & inhibitors<br/>fms-Like Tyrosine Kinase 3--antagonists & inhibitors