Combinatorial therapeutic activation with heparin and AICAR stimulates additive effects on utrophin A expression in dystrophic muscles. [electronic resource]
- Human molecular genetics Jan 2016
- 24-43 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1460-2083
10.1093/hmg/ddv444 doi
Aminoimidazole Carboxamide--analogs & derivatives Animals Cell Line Drug Therapy, Combination Heparin--therapeutic use Mice Mice, Inbred mdx Muscle, Skeletal--drug effects Muscular Dystrophy, Duchenne--drug therapy Ribonucleotides--therapeutic use Signal Transduction--drug effects Up-Regulation--drug effects Utrophin--biosynthesis p38 Mitogen-Activated Protein Kinases--metabolism