TY - GEN AU - Tibes,Raoul AU - Al-Kali,Aref AU - Oliver,Gavin R AU - Delman,Devora H AU - Hansen,Nanna AU - Bhagavatula,Keerthi AU - Mohan,Jayaram AU - Rakhshan,Fariborz AU - Wood,Thomas AU - Foran,James M AU - Mesa,Ruben A AU - Bogenberger,James M TI - The Hedgehog pathway as targetable vulnerability with 5-azacytidine in myelodysplastic syndrome and acute myeloid leukemia SN - 1756-8722 PY - 2016///0711 KW - Acute Disease KW - Aged KW - Aged, 80 and over KW - Anilides KW - pharmacology KW - Antimetabolites, Antineoplastic KW - Azacitidine KW - Biphenyl Compounds KW - Cell Line, Tumor KW - Cell Survival KW - drug effects KW - Chromosomes, Human, Pair 5 KW - genetics KW - Chromosomes, Human, Pair 7 KW - Drug Synergism KW - Female KW - HL-60 Cells KW - Hedgehog Proteins KW - High-Throughput Nucleotide Sequencing KW - methods KW - Humans KW - Leukemia, Myeloid KW - drug therapy KW - Male KW - Myelodysplastic Syndromes KW - Pyridines KW - RNA Interference KW - Signal Transduction N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1186/s13045-015-0211-8 ER -