TY  - GEN
AU  - Ngoh,Eyler N
AU  - Weisser,Shelley B
AU  - Lo,Young
AU  - Kozicky,Lisa K
AU  - Jen,Roger
AU  - Brugger,Hayley K
AU  - Menzies,Susan C
AU  - McLarren,Keith W
AU  - Nackiewicz,Dominika
AU  - van Rooijen,Nico
AU  - Jacobson,Kevan
AU  - Ehses,Jan A
AU  - Turvey,Stuart E
AU  - Sly,Laura M
TI  - Activity of SHIP, Which Prevents Expression of Interleukin 1β, Is Reduced in Patients With Crohn's Disease
SN  - 1528-0012
PY  - 2016///0603
KW  - Animals
KW  - Anti-Inflammatory Agents
KW  - pharmacology
KW  - Cells, Cultured
KW  - Class I Phosphatidylinositol 3-Kinases
KW  - Crohn Disease
KW  - diagnosis
KW  - Disease Models, Animal
KW  - Humans
KW  - Ileitis
KW  - Ileum
KW  - enzymology
KW  - Inositol Polyphosphate 5-Phosphatases
KW  - Interleukin-18
KW  - metabolism
KW  - Interleukin-1beta
KW  - genetics
KW  - Leukocytes, Mononuclear
KW  - Macrophages
KW  - Mice, 129 Strain
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Phosphatidylinositol 3-Kinases
KW  - Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Phosphoric Monoester Hydrolases
KW  - deficiency
KW  - Protein Kinase Inhibitors
KW  - Receptors, Interleukin-1
KW  - antagonists & inhibitors
KW  - Transcription, Genetic
KW  - Up-Regulation
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1053/j.gastro.2015.09.049
ER  -