Garcia-Barrantes, Pedro M <br/><br/>
Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 1: SAR of modifications to the central aryl core.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Nov 2015 
 - 5107-10 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2015.10.013  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Allosteric Regulation<br/>Animals<br/>Brain--metabolism<br/>Coumarins--blood<br/>Furans--blood<br/>Humans<br/>Microsomes, Liver--metabolism<br/>Phthalimides--blood<br/>Rats<br/>Receptors, Metabotropic Glutamate--agonists<br/>Stereoisomerism<br/>Structure-Activity Relationship