TY - GEN AU - Jain,Rajul K AU - Hong,David S AU - Naing,Aung AU - Wheler,Jennifer AU - Helgason,Thorunn AU - Shi,Nai-Yi AU - Gad,Yash AU - Kurzrock,Razelle TI - Novel phase I study combining G1 phase, S phase, and G2/M phase cell cycle inhibitors in patients with advanced malignancies SN - 1551-4005 PY - 2016///0829 KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - Antineoplastic Combined Chemotherapy Protocols KW - adverse effects KW - Bortezomib KW - administration & dosage KW - Computer Simulation KW - Disease Progression KW - Disease-Free Survival KW - Drug Administration Schedule KW - Female KW - G1 Phase Cell Cycle Checkpoints KW - drug effects KW - G2 Phase Cell Cycle Checkpoints KW - Humans KW - Kaplan-Meier Estimate KW - Male KW - Maximum Tolerated Dose KW - Middle Aged KW - Models, Biological KW - Molecular Targeted Therapy KW - Neoplasms KW - drug therapy KW - S Phase Cell Cycle Checkpoints KW - Sirolimus KW - Texas KW - Time Factors KW - Topotecan KW - Treatment Outcome KW - Young Adult N1 - Publication Type: Clinical Trial, Phase I; Journal Article UR - https://doi.org/10.1080/15384101.2015.1090065 ER -