Surmeli, Zeki

Combination of zoledronic acid and serine/threonine phosphatase inhibitors induces synergistic cytotoxicity and apoptosis in human breast cancer cells via inhibition of PI3K/Akt pathway. [electronic resource] - Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine Mar 2016 - 3665-73 p. digital

Publication Type: Journal Article

1423-0380

10.1007/s13277-015-3265-x doi


Apoptosis--drug effects
Blotting, Western
Breast Neoplasms--metabolism
Cell Line, Tumor
Cell Survival--drug effects
Diphosphonates--pharmacology
Dose-Response Relationship, Drug
Drug Synergism
Enzyme Inhibitors--pharmacology
Female
Humans
Imidazoles--pharmacology
MCF-7 Cells
Marine Toxins
Okadaic Acid--pharmacology
Oxazoles--pharmacology
Phosphatidylinositol 3-Kinases--metabolism
Phosphoprotein Phosphatases--antagonists & inhibitors
Proto-Oncogene Proteins c-akt--metabolism
Signal Transduction--drug effects
Zoledronic Acid