TY - GEN AU - Zou,Zheng-Zhi AU - Nie,Pei-Pei AU - Li,Ya-Wei AU - Hou,Ben-Xin AU - Shi,Xin-Peng AU - Ma,Zhao-Kui AU - Han,Bao-Wei AU - Luo,Xiao-Yong TI - Synergistic induction of apoptosis by salinomycin and gefitinib through lysosomal and mitochondrial dependent pathway overcomes gefitinib resistance in colorectal cancer SN - 1949-2553 PY - 2017///0915 KW - Animals KW - Apoptosis KW - drug effects KW - Cathepsin B KW - metabolism KW - Cathepsin D KW - Cell Line, Tumor KW - Cell Survival KW - Colorectal Neoplasms KW - drug therapy KW - Drug Resistance, Neoplasm KW - Drug Synergism KW - Gefitinib KW - Humans KW - Lysosomes KW - Membrane Potential, Mitochondrial KW - Mice KW - Mice, Nude KW - Mitochondria KW - Pyrans KW - therapeutic use KW - Quinazolines KW - Reactive Oxygen Species KW - Signal Transduction KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article UR - https://doi.org/10.18632/oncotarget.5628 ER -