Zou, Zheng-Zhi <br/><br/>
Synergistic induction of apoptosis by salinomycin and gefitinib through lysosomal and mitochondrial dependent pathway overcomes gefitinib resistance in colorectal cancer.  [electronic resource] 

 -  Oncotarget  Apr 2017 
 - 22414-22432 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1949-2553 
<br/><br/><label>Standard No.: </label>10.18632/oncotarget.5628  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apoptosis--drug effects<br/>Cathepsin B--metabolism<br/>Cathepsin D--metabolism<br/>Cell Line, Tumor<br/>Cell Survival<br/>Colorectal Neoplasms--drug therapy<br/>Drug Resistance, Neoplasm--drug effects<br/>Drug Synergism<br/>Gefitinib<br/>Humans<br/>Lysosomes--drug effects<br/>Membrane Potential, Mitochondrial--drug effects<br/>Mice<br/>Mice, Nude<br/>Mitochondria--metabolism<br/>Pyrans--therapeutic use<br/>Quinazolines--therapeutic use<br/>Reactive Oxygen Species--metabolism<br/>Signal Transduction<br/>Xenograft Model Antitumor Assays