TY - GEN AU - Waning,David L AU - Mohammad,Khalid S AU - Reiken,Steven AU - Xie,Wenjun AU - Andersson,Daniel C AU - John,Sutha AU - Chiechi,Antonella AU - Wright,Laura E AU - Umanskaya,Alisa AU - Niewolna,Maria AU - Trivedi,Trupti AU - Charkhzarrin,Sahba AU - Khatiwada,Pooja AU - Wronska,Anetta AU - Haynes,Ashley AU - Benassi,Maria Serena AU - Witzmann,Frank A AU - Zhen,Gehua AU - Wang,Xiao AU - Cao,Xu AU - Roodman,G David AU - Marks,Andrew R AU - Guise,Theresa A TI - Excess TGF-β mediates muscle weakness associated with bone metastases in mice SN - 1546-170X PY - 2016///0216 KW - Absorptiometry, Photon KW - Animals KW - Bone Neoplasms KW - diagnostic imaging KW - Breast Neoplasms KW - metabolism KW - Calcium KW - Calcium Signaling KW - Camurati-Engelmann Syndrome KW - Cell Line, Tumor KW - Disease Models, Animal KW - Female KW - Humans KW - Lung Neoplasms KW - MCF-7 Cells KW - Male KW - Mice KW - Mice, Nude KW - Mice, SCID KW - Multiple Myeloma KW - Muscle Contraction KW - Muscle Proteins KW - Muscle Strength KW - Muscle Weakness KW - etiology KW - Muscle, Skeletal KW - NADPH Oxidase 4 KW - NADPH Oxidases KW - genetics KW - Neoplasms KW - complications KW - Osteolysis KW - Oxidation-Reduction KW - Prostatic Neoplasms KW - Ryanodine Receptor Calcium Release Channel KW - Transforming Growth Factor beta KW - Up-Regulation KW - X-Ray Microtomography N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/nm.3961 ER -