TY - GEN AU - Yamamoto,Satoshi AU - Ooshima,Yuki AU - Nakata,Mitsugu AU - Yano,Takashi AU - Nishimura,Naoya AU - Nishigaki,Ryuuichi AU - Satomi,Yoshinori AU - Matsumoto,Hirokazu AU - Matsumoto,Yoshio AU - Takeyama,Michiyasu TI - Efficient gene-targeting in rat embryonic stem cells by CRISPR/Cas and generation of human kynurenine aminotransferase II (KAT II) knock-in rat SN - 1573-9368 PY - 2016///0823 KW - Animals KW - Base Sequence KW - Blotting, Southern KW - CRISPR-Cas Systems KW - Cells, Cultured KW - Embryonic Stem Cells KW - cytology KW - Female KW - Gene Targeting KW - Homologous Recombination KW - Humans KW - Kynurenic Acid KW - metabolism KW - Male KW - Molecular Sequence Data KW - RNA, Messenger KW - genetics KW - Rats KW - Rats, Long-Evans KW - Rats, Wistar KW - Real-Time Polymerase Chain Reaction KW - Reverse Transcriptase Polymerase Chain Reaction KW - Sequence Homology, Nucleic Acid KW - Transaminases N1 - Publication Type: Journal Article UR - https://doi.org/10.1007/s11248-015-9909-1 ER -