TY - GEN AU - Keenan,Melissa M AU - Liu,Beiyu AU - Tang,Xiaohu AU - Wu,Jianli AU - Cyr,Derek AU - Stevens,Robert D AU - Ilkayeva,Olga AU - Huang,Zhiqing AU - Tollini,Laura A AU - Murphy,Susan K AU - Lucas,Joseph AU - Muoio,Deborah M AU - Kim,So Young AU - Chi,Jen-Tsan TI - ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate SN - 1553-7404 PY - 2016///0429 KW - ATP Citrate (pro-S)-Lyase KW - antagonists & inhibitors KW - Acetyl-CoA Carboxylase KW - Adenovirus E1A Proteins KW - biosynthesis KW - Apoptosis KW - genetics KW - Cell Hypoxia KW - Cell Line, Tumor KW - Gene Expression Regulation, Neoplastic KW - drug effects KW - Humans KW - Ketoglutaric Acids KW - metabolism KW - Neoplasms KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-ets KW - Tumor Microenvironment N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1371/journal.pgen.1005599 ER -