TY  - GEN
AU  - John,Jubi
AU  - Kim,Youngju
AU  - Bennett,Nicholas
AU  - Das,Kalyan
AU  - Liekens,Sandra
AU  - Naesens,Lieve
AU  - Arnold,Eddy
AU  - Maguire,Anita R
AU  - Götte,Matthias
AU  - Dehaen,Wim
AU  - Balzarini,Jan
TI  - Pronounced Inhibition Shift from HIV Reverse Transcriptase to Herpetic DNA Polymerases by Increasing the Flexibility of α-Carboxy Nucleoside Phosphonates
SN  - 1520-4804
PY  - 2016///0202
KW  - Antiviral Agents
KW  - chemical synthesis
KW  - DNA Polymerase I
KW  - antagonists & inhibitors
KW  - DNA Polymerase beta
KW  - DNA Primers
KW  - Drug Design
KW  - HIV Reverse Transcriptase
KW  - HIV-1
KW  - drug effects
KW  - Herpesvirus 3, Human
KW  - Humans
KW  - Molecular Conformation
KW  - Nucleic Acid Synthesis Inhibitors
KW  - Organophosphonates
KW  - Plasmids
KW  - genetics
KW  - Reverse Transcriptase Inhibitors
KW  - Simplexvirus
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/acs.jmedchem.5b01180
ER  -