Shao, Fang-Yuan <br/><br/>
B5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy.  [electronic resource] 

 -  Oncotarget  Oct 2015 
 - 30939-56 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1949-2553 
<br/><br/><label>Standard No.: </label>10.18632/oncotarget.5132  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Autophagy--drug effects<br/>Blotting, Western<br/>Cell Cycle--drug effects<br/>Cell Proliferation--drug effects<br/>Curcumin--analogs & derivatives<br/>Female<br/>Fluorescent Antibody Technique<br/>Humans<br/>Immunoenzyme Techniques<br/>Immunoprecipitation<br/>Membrane Potential, Mitochondrial--drug effects<br/>Mitochondria--drug effects<br/>RNA, Messenger--genetics<br/>Reactive Oxygen Species--metabolism<br/>Real-Time Polymerase Chain Reaction<br/>Reverse Transcriptase Polymerase Chain Reaction<br/>Signal Transduction--drug effects<br/>Thioredoxin-Disulfide Reductase--antagonists & inhibitors<br/>Tumor Cells, Cultured<br/>Uterine Cervical Neoplasms--drug therapy