TY  - GEN
AU  - Quast,Isaak
AU  - Keller,Christian W
AU  - Maurer,Michael A
AU  - Giddens,John P
AU  - Tackenberg,Björn
AU  - Wang,Lai-Xi
AU  - Münz,Christian
AU  - Nimmerjahn,Falk
AU  - Dalakas,Marinos C
AU  - Lünemann,Jan D
TI  - Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity
SN  - 1558-8238
PY  - 2016///0222
KW  - Animals
KW  - Antibody-Dependent Cell Cytotoxicity
KW  - Antigens, CD20
KW  - immunology
KW  - B-Lymphocytes
KW  - Burkitt Lymphoma
KW  - pathology
KW  - Cell Line, Tumor
KW  - Complement C1q
KW  - Complement Pathway, Classical
KW  - Complement System Proteins
KW  - Cytotoxicity, Immunologic
KW  - Glycosylation
KW  - Humans
KW  - Immunoglobulin G
KW  - chemistry
KW  - Immunoglobulin gamma-Chains
KW  - Immunoglobulins, Intravenous
KW  - therapeutic use
KW  - Killer Cells, Natural
KW  - Lymphocyte Depletion
KW  - Mice
KW  - Myelin-Oligodendrocyte Glycoprotein
KW  - N-Acetylneuraminic Acid
KW  - Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
KW  - Protein Processing, Post-Translational
KW  - Receptors, IgG
KW  - Rituximab
N1  - Publication Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1172/JCI82695
ER  -