TY  - GEN
AU  - Mohlin,Sofie
AU  - Hamidian,Arash
AU  - von Stedingk,Kristoffer
AU  - Bridges,Esther
AU  - Wigerup,Caroline
AU  - Bexell,Daniel
AU  - Påhlman,Sven
TI  - PI3K-mTORC2 but not PI3K-mTORC1 regulates transcription of HIF2A/EPAS1 and vascularization in neuroblastoma
SN  - 1538-7445
PY  - 2016///0225
KW  - Adaptor Proteins, Signal Transducing
KW  - genetics
KW  - Animals
KW  - Antigens, CD
KW  - Basic Helix-Loop-Helix Transcription Factors
KW  - biosynthesis
KW  - Cell Line, Tumor
KW  - Female
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Hypoxia-Inducible Factor 1, alpha Subunit
KW  - Mechanistic Target of Rapamycin Complex 1
KW  - Mechanistic Target of Rapamycin Complex 2
KW  - Mice
KW  - Mice, Nude
KW  - Multiprotein Complexes
KW  - metabolism
KW  - Neovascularization, Pathologic
KW  - Neuroblastoma
KW  - blood supply
KW  - Phosphatidylinositol 3-Kinases
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Proto-Oncogene Proteins c-akt
KW  - RNA Interference
KW  - RNA, Messenger
KW  - RNA, Small Interfering
KW  - Receptor, IGF Type 1
KW  - Receptor, IGF Type 2
KW  - Receptor, Insulin
KW  - Receptors, Somatomedin
KW  - Regulatory-Associated Protein of mTOR
KW  - Signal Transduction
KW  - physiology
KW  - TOR Serine-Threonine Kinases
KW  - Transcription, Genetic
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1158/0008-5472.CAN-15-0708
ER  -