Mohlin, Sofie <br/><br/>
PI3K-mTORC2 but not PI3K-mTORC1 regulates transcription of HIF2A/EPAS1 and vascularization in neuroblastoma.  [electronic resource] 

 -  Cancer research  Nov 2015 
 - 4617-28 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1538-7445 
<br/><br/><label>Standard No.: </label>10.1158/0008-5472.CAN-15-0708  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adaptor Proteins, Signal Transducing--genetics<br/>Animals<br/>Antigens, CD--genetics<br/>Basic Helix-Loop-Helix Transcription Factors--biosynthesis<br/>Cell Line, Tumor<br/>Female<br/>Gene Expression Regulation, Neoplastic<br/>Humans<br/>Hypoxia-Inducible Factor 1, alpha Subunit--biosynthesis<br/>Mechanistic Target of Rapamycin Complex 1<br/>Mechanistic Target of Rapamycin Complex 2<br/>Mice<br/>Mice, Nude<br/>Multiprotein Complexes--metabolism<br/>Neovascularization, Pathologic--genetics<br/>Neuroblastoma--blood supply<br/>Phosphatidylinositol 3-Kinases--metabolism<br/>Phosphoinositide-3 Kinase Inhibitors<br/>Proto-Oncogene Proteins c-akt--genetics<br/>RNA Interference<br/>RNA, Messenger--biosynthesis<br/>RNA, Small Interfering<br/>Receptor, IGF Type 1<br/>Receptor, IGF Type 2--genetics<br/>Receptor, Insulin--genetics<br/>Receptors, Somatomedin--genetics<br/>Regulatory-Associated Protein of mTOR<br/>Signal Transduction--physiology<br/>TOR Serine-Threonine Kinases--metabolism<br/>Transcription, Genetic--genetics