TY  - GEN
AU  - Benek,Ondrej
AU  - Soukup,Ondrej
AU  - Pasdiorova,Marketa
AU  - Hroch,Lukas
AU  - Sepsova,Vendula
AU  - Jost,Petr
AU  - Hrabinova,Martina
AU  - Jun,Daniel
AU  - Kuca,Kamil
AU  - Zala,Dominykas
AU  - Ramsay,Rona R
AU  - Marco-Contelles,José
AU  - Musilek,Kamil
TI  - Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease
SN  - 1860-7187
PY  - 2017///0327
KW  - Acetylcholinesterase
KW  - chemistry
KW  - Alzheimer Disease
KW  - drug therapy
KW  - Blood-Brain Barrier
KW  - metabolism
KW  - Cell Survival
KW  - drug effects
KW  - Cholinesterase Inhibitors
KW  - chemical synthesis
KW  - Drug Design
KW  - Hep G2 Cells
KW  - Humans
KW  - Indoles
KW  - Inhibitory Concentration 50
KW  - Ligands
KW  - Monoamine Oxidase
KW  - Monoamine Oxidase Inhibitors
KW  - Quinolines
KW  - Structure-Activity Relationship
KW  - Tacrine
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1002/cmdc.201500383
ER  -